Anticoagulation, endocrine and GI
Heparin drip
UFH
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Heparin vs Warfarin: aPTT vs INR, HIT, Bridging, Antidotes and DOAC Reversal
Dosing
| Start | VTE: 80 units/kg bolus, then 18 units/kg/h. ACS: 60 units/kg bolus (max 4,000), then 12 units/kg/h (max 1,000 units/h) |
|---|---|
| Titrate | Per nomogram by aPTT or anti-Xa, usually every 6 hours |
| Maximum | ACS starting rate up to 1,000 units/h |
| Common bags | 25,000 units in 250 mL (100 units/mL); 25,000 units in 500 mL (50 units/mL) |
| Dose units | units/kg/h, units/h |
Line and administration
- High-alert drug: independent double-check of pump and bag
Watch for
- Bleeding
- Platelets: HIT on day 5–10
Heparin: full drug monographIndications, mechanism, pharmacokinetics, cautions and every dose the app lists.
In the one-pagers
- Pulmonary EmbolismDiagnosis: unstable vs stable: Shock or hypotension: Heparin now; bedside echo or CTPA, whichever is faster
- Impella Heart PumpPurge system: Add heparin 25 or 50 units/mL, or bicarbonate 25 or 50 mEq/L if heparin is contraindicated. Never both; no other anticoagulant.
- ECMO EssentialsMonitoring and anticoagulation: Anti-Xa on UFH: 0.3–0.7 IU/mL
- IABP ManagementNursing care: Anticoagulation per protocol; heparin use varies
- ACS and STEMIInitial medications: Heparin (UFH): PCI: 70-100 units/kg to ACT; lytic: 60 units/kg (max 4,000): Or bivalirudin, enoxaparin
- LVAD BasicsComplications: Pump thrombosis: Rising power, high LDH and free Hgb, dark urine: IV heparin or bivalirudin; pump exchange if refractory
Practice Pulmonary Embolism questions free8 exam-style questions with rationales on the topic where heparin comes up most. No account or download needed.
Other anticoagulation, endocrine and gi
- Insulin (regular)
- Amiodarone
- Diltiazem
- Octreotide
- Pantoprazole
- Furosemide
- Argatroban
- Bivalirudin
- Procainamide
- Lidocaine
- Magnesium sulfate
- Naloxone
- Eptifibatide
- Bumetanide
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For education and exam preparation only. Follow your institution’s protocols. Study aid: check every dose against your local protocols and medical direction, the bag label and your pump.