Vasopressors and inotropes
Angiotensin II (Giapreza) drip
Giapreza
Dosing
| Start | 20 ng/kg/min |
|---|---|
| Titrate | Up to 15 ng/kg/min every 5 minutes |
| Maximum | 80 ng/kg/min in the first 3 hours, then 40 |
| Common bags | 2.5 mg in 250 mL (10 mcg/mL); 2.5 mg in 500 mL (5 mcg/mL) |
| Dose units | ng/kg/min |
Line and administration
- Central line advised
Watch for
- Thrombosis: give VTE prophylaxis
- Doses are nanograms
Angiotensin II: full drug monographIndications, mechanism, pharmacokinetics, cautions and every dose the app lists.
In the one-pagers
- Vasopressors and InotropesReceptors and effects: Angiotensin II: AT1: ↔ / ↔ / ↑↑
- Shock Types at a GlanceResuscitation endpoints, mixed and late shock: Refractory shock, loosely a norepinephrine-equivalent dose above 0.5–1 mcg/kg/min with persistent hypoperfusion, calls for a checklist: confirm the infusion is running and the arterial line is accurate, repeat the echo, give hydrocortisone, add vasopressin, correct ionized calcium, severe acidosis and hypothermia, consider angiotensin II or methylene
Practice Vasopressors and Inotropes questions free8 exam-style questions with rationales on the topic where angiotensin ii comes up most. No account or download needed.
Other vasopressors and inotropes
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For education and exam preparation only. Follow your institution’s protocols. Study aid: check every dose against your local protocols and medical direction, the bag label and your pump.