First five minutes

Low Urine Output Algorithm

Catheter first, then pressure, volume, the kidney and who to call

Reviewed by Alex G, BSN, RN, CEN, CCRN, CMC, NREMT-P · From the Reference tab of the app

Each step lists what to do, then the choices that lead on. In the app the algorithm is tapped through one decision at a time.

1 Check the patient first

  • Vitals now: BP and MAP, HR, temperature, SpO₂, mental status; low urine can be the first sign of shock
  • Work out the goal: 0.5 mL/kg/h or more (35 mL/h at 70 kg); add up the last 6 hourly volumes
  • Shock, new confusion, breathlessness, K 6 or more or peaked T waves: call the provider now (rapid response outside the ICU)

Next: is it real? → step 2

2 Is the output really low?

  • Foley: look for kinks, dependent loops, a clamp or closed port, a full bag; keep the bag below the bladder
  • Bladder scan: urine pooling in the bladder despite a Foley means it is blocked or misplaced
  • No Foley: a full bladder on the scan (often 400 mL or more) is retention
  • Check the charting: missed hourly totals, urine sitting in the tubing, other outputs (nephrostomy, urostomy)

Blocked catheter or full bladder → step 3Real: catheter patent, bladder empty → step 4

3 Drainage problem: fix it

  • Straighten kinks and loops; empty the bag; keep it below the bladder and off the floor
  • Flush or replace a blocked catheter per policy; clots or hematuria: three-way catheter and irrigation per order
  • Retention without a Foley: catheterize per order and record the volume drained
  • After a large retention: watch for brisk diuresis (over 200 mL/h) and replace losses per order

Still low once draining freely → step 4

4 Is the MAP high enough for the kidneys?

  • Most kidneys need MAP 65 or more; a usually hypertensive patient may need more: compare with the usual BP
  • Low flow can starve the kidneys at a normal MAP: cool skin, slow capillary refill, low cardiac output
  • Kidney perfusion is roughly MAP minus CVP or bladder pressure: congestion and a tense abdomen hurt too

MAP under 65 or well below the usual → step 5MAP at target → step 6

5 Low MAP: restore it first

  • Treat it as new hypotension: confirm the reading, check perfusion, find the cause (New Hypotension algorithm)
  • Fluid only if fluid responsive and not overloaded; otherwise a vasopressor to the MAP target per order
  • Usually hypertensive: ask whether a higher MAP target suits this patient
  • Recheck urine output 1–2 hours after the MAP is restored

Next: volume status → step 6

6 What is the volume status?

  • Dry: losses (drains, NG, diarrhea, bleeding), negative balance, flat neck veins, tachycardia, dry mucosa
  • Wet: edema, crackles, high CVP, rising O₂ need, weight up, large positive balance
  • Unsure: passive leg raise; stroke volume or cardiac output up 10% or more predicts a fluid response

Dry or fluid responsive, and not overloaded → step 7Overloaded, or not fluid responsive → step 8

7 Fluid challenge

  • Balanced crystalloid 250–500 mL over 10–15 min per order; reassess after each bolus
  • Stop for crackles, rising O₂ need or JVD, and tell the provider
  • Replace ongoing losses; hold diuretics while dry
  • Urine picks up within 1–2 hours: likely prerenal; keep replacing losses and report the response

Next: how long has it been low? → step 9

8 Overloaded or not responsive: no more fluid

  • More fluid will not restore urine and can harm: a high CVP itself lowers kidney perfusion
  • Overload: loop diuretic per order (furosemide 40–80 mg IV, more if on a home dose) to treat the overload, not the number
  • Cold and congested (failing heart): the kidneys need cardiac output; inotrope or cardiology per the provider
  • Overload with high potassium or acidosis may need dialysis: ask about nephrology

Next: how long has it been low? → step 9

9 How low, for how long? (KDIGO)

  • AKI stage 1: under 0.5 mL/kg/h for 6–12 h, or creatinine up 0.3 mg/dL in 48 h or 1.5 times baseline
  • Stage 2: under 0.5 mL/kg/h for 12 h or more, or creatinine 2–2.9 times baseline
  • Stage 3: under 0.3 mL/kg/h for 24 h, anuria for 12 h, creatinine 3 times baseline or 4 mg/dL or more, or dialysis started
  • Sudden anuria: recheck the catheter, then think obstruction or a blocked renal artery (ultrasound)

Next: find the cause → step 10

10 Find the cause

  • Prerenal: low volume, low MAP or low cardiac output; concentrated urine, urine sodium under 20
  • Intrinsic: sepsis, prolonged hypotension, contrast, nephrotoxic drugs, rhabdomyolysis (dark urine, high CK)
  • Postrenal: catheter, prostate, clots, stones; renal ultrasound for hydronephrosis
  • Tense abdomen, large positive balance, abdominal surgery or rising airway pressures: measure bladder pressure

Possible abdominal compartment syndrome → step 11Next: stop nephrotoxins, send labs → step 12

11 Bladder pressure (intra-abdominal pressure)

  • Supine; zero the transducer at the mid-axillary line at the iliac crest; instill no more than 25 mL saline (closed kit per policy)
  • Read in mmHg at end-expiration, with the abdominal muscles relaxed
  • 12 mmHg or more is intra-abdominal hypertension; over 20 with new organ failure is abdominal compartment syndrome
  • Compartment syndrome: call the surgeon now; NG and rectal decompression, deeper analgesia and sedation, no positive balance

Next: stop nephrotoxins, send labs → step 12

12 Stop nephrotoxins and send labs

  • Hold or question: NSAIDs, aminoglycosides, amphotericin, IV contrast, ACE inhibitors and ARBs; vancomycin by levels
  • Ask pharmacy to renally dose every drug; hold metformin; no renal-dose dopamine
  • Pause potassium supplements and potassium in IV fluids until potassium and urine output are reviewed
  • Send BMP (creatinine, potassium, bicarbonate), magnesium, phosphate, CBC, urinalysis with microscopy
  • Also urine sodium and creatinine (FENa), CK, lactate and a blood gas; renal ultrasound if obstruction is possible

Next: when to call → step 13

13 When to call, and what to report

  • Call now: MAP under 65, anuria, K 6 or more or ECG changes, pH under 7.15, overload with hypoxemia, new confusion
  • Report within the hour: under 0.5 mL/kg/h for 2 hours in a row (or per unit parameters), or creatinine up 0.3 mg/dL
  • S and B: hourly volumes for 6 h in mL and mL/kg/h, how you confirmed them, baseline creatinine, fluid balance, contrast and nephrotoxins
  • A and R: MAP, volume status and fluid response, bladder pressure, K and creatinine; ask for orders, and nephrology if dialysis may be needed

End of this path.

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