Blood pressure and rate control
Labetalol (Trandate) drip
Trandate
Dosing
| Start | 0.5–2 mg/min, or 20 mg IV push then 20–80 mg every 10 minutes |
|---|---|
| Titrate | By blood pressure |
| Maximum | 300 mg total (label) |
| Common bags | 200 mg in 200 mL (1 mg/mL); 500 mg in 250 mL (2 mg/mL) |
| Dose units | mg/min, mg/h |
Line and administration
- Peripheral or central
Watch for
- Bradycardia and heart block
- Bronchospasm
- Avoid in decompensated heart failure
Labetalol: full drug monographIndications, mechanism, pharmacokinetics, cautions and every dose the app lists.
In the one-pagers
- Aortic Dissection and Hypertensive EmergencyAortic dissection: Beta-blocker FIRST (esmolol or labetalol), then a vasodilator (nicardipine, clevidipine or nitroprusside) if BP stays high
- Obstetric EmergenciesPreeclampsia and eclampsia: Labetalol IV: 20 mg over 2 min: 40 mg, then 80 mg every 10 min; max 300 mg
Practice Aortic Dissection and Hypertensive Emergency questions free19 exam-style questions with rationales on the topic where labetalol comes up most. No account or download needed.
Other blood pressure and rate control
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For education and exam preparation only. Follow your institution’s protocols. Study aid: check every dose against your local protocols and medical direction, the bag label and your pump.