Sedation, analgesia and paralysis
Hydromorphone (Dilaudid) drip
Dilaudid
Dosing
| Start | 0.5–1 mg/h (PADIS range 0.5–3 mg/h) |
|---|---|
| Titrate | 0.25–0.5 mg/h, with boluses every 15–30 minutes |
| Maximum | No ceiling; most patients need under 3–4 mg/h |
| Common bags | 20 mg in 100 mL (200 mcg/mL); 50 mg in 50 mL (1 mg/mL) |
| Dose units | mg/h |
Line and administration
- Peripheral or central
Watch for
- About seven times as potent as morphine: check the concentration
- Respiratory depression
- Metabolite build-up in kidney failure (agitation, myoclonus)
Hydromorphone: full drug monographIndications, mechanism, pharmacokinetics, cautions and every dose the app lists.
Other sedation, analgesia and paralysis
- Propofol
- Dexmedetomidine
- Midazolam
- Fentanyl
- Cisatracurium
- Ketamine
- Rocuronium
- Vecuronium
- Pentobarbital
- Remifentanil
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For education and exam preparation only. Follow your institution’s protocols. Study aid: check every dose against your local protocols and medical direction, the bag label and your pump.